H2S mitigates severe acute pancreatitis through the PI3K/AKT-NF-κB pathway in vivo

Figure 3 Levels of p-AKT (A), IκBα protein expression (B) and nuclear factor-κB activity in vivo (C). Western blot and EMSA analyses of the protein expression and NF-κB activity after treatment with L-Arg and NaHS or PAG and the PI₃K inhibitor wortmannin. ^aP < 0.05 vs the control; ^cP < 0.05 vs the severe acute pancreatitis (SAP) group; ^eP < 0.05 vs the 5 mg/kg NaHS + SAP group; ^gP< 0.05 vs the 100 mg/kg NaHS + SAP group.