Influence of proton pump inhibitors on gastritis diagnosis and pathologic gastric changes

Table 2 Effect of proton pump inhibitors exposure on Helicobacter pylori detection, density and intestinal metaplasia n (%)

	Previous PPI exposuren = 155	No PPI exposuren = 145	P value
H. pylori gastritis	53 (34.20)	103 (71)	< 0.001
Inactive chronic gastritis	102 (65.80)	42 (29)	< 0.001
H. pylori density
Low density	40 (25.80)	52 (35.90)	< 0.001
High density	13 (8.38)	51 (35.17)	< 0.001
Intestinal metaplasia	10 (6.50)	2 (1.40)	0.023

PPI: Proton pump inhibitor; H. pylori: Helicobacter pylori.