Copyright
©The Author(s) 2015.
World J Gastroenterol. Apr 21, 2015; 21(15): 4592-4598
Published online Apr 21, 2015. doi: 10.3748/wjg.v21.i15.4592
Published online Apr 21, 2015. doi: 10.3748/wjg.v21.i15.4592
Table 2 Age at diagnosis and clincopathologic characteristics of patients with gastric cancer according to affected first-degree family member n (%)
Father | Mother | Sibling | P value | |||
n = 349 (37.8%) | n = 229 (24.8%) | n = 319 (34.5%) | Father vs mother | Father vs sibling | Mother vs sibling | |
Age at diagnosis, yr (mean ± SD) | 54.4 ± 10.4 | 57.2 ± 10.0 | 62.2 ± 9.8 | 0.0021 | < 0.0011 | < 0.0011 |
Male | 252 (72.2) | 137 (59.8) | 213 (66.8) | 0.0022 | 0.1272 | 0.0952 |
Female | 97 (27.8) | 92 (40.2) | 106 (33.2) | |||
Tumor diameter (mean ± SD) | 3.9 ± 2.8 | 3.9 ± 2.4 | 3.8 ± 2.4 | 0.9881 | 0.6611 | 0.6611 |
Lauren’s classification | 0.7642 | 0.0032 | 0.0212 | |||
Intestinal | 191 (54.7) | 132 (57.6) | 205 (64.3) | |||
Diffuse | 130 (37.3) | 81 (35.4) | 80 (25.1) | |||
Mixed | 28 (8.0) | 16 (7.0) | 34 (10.7) | |||
H. pylori infection status | 0.5302 | 0.5192 | 0.8272 | |||
Current | 241 (69.1) | 150 (65.5) | 206 (64.6) | |||
Past | 43 (12.3) | 25 (10.9) | 42 (13.2) | |||
Negative | 37 (10.6) | 32 (14.0) | 45 (14.1) | |||
Not available | 28 (8.0) | 22 (9.6) | 26 (8.2) | |||
Gastric cancer stage | 0.1932 | 0.7462 | 0.1862 | |||
Stage 1 | 254 (72.8) | 166 (72.5) | 235 (73.7) | |||
Stage 2 | 41 (11.7) | 28 (12.2) | 43 (13.5) | |||
Stage 3 | 35 (10.0) | 30 (13.1) | 27 (8.5) | |||
Stage 4 | 19 (5.4) | 5 (2.2) | 14 (4.4) |
- Citation: Kwak HW, Choi IJ, Kim CG, Lee JY, Cho SJ, Eom BW, Yoon HM, Joo J, Ryu KW, Kim YW. Individual having a parent with early-onset gastric cancer may need screening at younger age. World J Gastroenterol 2015; 21(15): 4592-4598
- URL: https://www.wjgnet.com/1007-9327/full/v21/i15/4592.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i15.4592