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©The Author(s) 2015.
World J Gastroenterol. Apr 21, 2015; 21(15): 4466-4490
Published online Apr 21, 2015. doi: 10.3748/wjg.v21.i15.4466
Published online Apr 21, 2015. doi: 10.3748/wjg.v21.i15.4466
Table 8 Clinical trials with herbal traditional Chinese medicine preparations for colon carcinoma
Ref. | Patients | Treatment | Control | Outcome | Remarks |
Zhou et al[146], 2009 | 163 pat.; colon carcinoma, no information on stage | 105 pat.; 40 mL/d Zhao's Weitiao No. 3, 30 d = 1 cycle, 4-6 cycles | 58 pat.; 40 mL/d Zhao's Weitiao No. 3 + OLF protocol, cycles as treatment | For tumor mass, CEA control is better, for symptom and QoL treatment is better | Assignment according to patients wish; OLF: oxaliplatin, 5-FU + leucovorin. Conclusions incorrect |
Liu et al[147], 2005 | 64 pat.; colon carcinoma postoperatively | 43 pat.; chemotherapy + Jianpi Huoxue herbs, 3 mo, no dose given | 21 pat.; chemotherapy, 3 mo | Remission 39.5% treatment, 33.3 control; Pi deficiency treatment P < 0.01 | Randomized study; effects only in Chinese symptoms |
Guo[149], 1999 | 68 pat.; large intestinal cancer | 38 pat.; chemotherapy + Fu Zheng Yiai decoction, no dose, duration | 30 pat.; chemotherapy, no dose, duration | Physical strength, survival time, rate, recurrence sign better | No specific data given |
Cao et al[148], 1994 | 79 pat.; diverse advanced carcinoma incl. colon carcinoma | LAK/IL-2 + Lycium Barbarum polysaccharides; no dose, duration | LKA/IL-2 | Response rate, remission, NK, LAK cell activity sign. better | 4 dropouts. No specific data |
Li[150], 1992 | 176 pat.; malignant tumor of digestive tract | Chemotherapy + Shen Qi injection, no further details given | Chemotherapy, no further details given | No leukocyte decrease, improved cellular immunological function | No specific data given |
- Citation: Teschke R, Wolff A, Frenzel C, Eickhoff A, Schulze J. Herbal traditional Chinese medicine and its evidence base in gastrointestinal disorders. World J Gastroenterol 2015; 21(15): 4466-4490
- URL: https://www.wjgnet.com/1007-9327/full/v21/i15/4466.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i15.4466