Early activated hepatic stellate cell-derived molecules reverse acute hepatic injury

Figure 6 Differences between hepatic stellate cell-CM (5d) and hepatic stellate cell-CM (P3) in cytokine composition. Serum-free hepatic stellate cell (HSC)-CM was analyzed using an antibody array for 144 specified proteins. A: Densitometry of spotted antibody array results. Data are presented as spot intensity relative to the negative control and normalized to the positive control. ¹Molecules whose concentrations in HSC-CM (5d) were more than twice as high as in HSC-CM (P3); ²molecules whose concentrations in HSC-CM (P3) were more than twice as high as in HSC-CM (5d). Pie chart showing cluster analysis of HSC (5d) secreted proteins (B) and HSC (P3) secreted proteins (C) based on reported function.