Early activated hepatic stellate cell-derived molecules reverse acute hepatic injury

Figure 2 Ultrastructure of hepatic stellate cells observed under a transmission electron microscope. A: HSCs contained lipid droplets (L) around the nucleus (N) after primarily cultured for 24 h; B: Primary HSCs were characterized by decreased lipid droplets and a moderate amount of rough endoplasmic reticulum (ER) and mitochondria (M) when cultured for 5 d; C: HSCs (P3) exhibited marked hypertrophy of rough endoplasmic reticulum and microfilaments, but no lipid droplets. Black arrows point to microfilaments. HSC: Hepatic stellate cell.