Basic Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Apr 14, 2015; 21(14): 4136-4149
Published online Apr 14, 2015. doi: 10.3748/wjg.v21.i14.4136
Figure 2
Figure 2 Germline variants identified in known colorectal cancer predisposing genes and genes likely to play a role in colorectal cancer development. The genes are listed on the left hand side and the patient samples on top. Patient samples from the same families are marked (bars). Known colorectal cancer (CRC) predisposing genes are marked by shading (left). The shades at the right hand side of the figure indicate functional (groups of) genes considered to play a role in CRC development. The different variant types are indicated in colors (right). The red-triangle/green-triangle square in sample 180-1 indicates the presence of one MUTYH nonsense and one MUTYH missense mutation.