Is cholecystectomy a reasonable treatment option for simple gallbladder polyps larger than 10 mm?

Table 2 Predictors of gallbladder cancer (multiple logistic regression analysis)

Variables	GB cancer
	OR (95%CI)	P value
Female	0.615 (0.276-1.370)	0.234
Size	1.516 (1.356-1.694)	< 0.001
Number of polyps	0.812 (0.531-1.244)	0.339
Age	1.120 (1.078-1.164)	< 0.001
Symptoms1	5.019 (1.649-15.276)	0.005
BMI	1.004 (0.995-1.014)	0.383
Total cholesterol	0.991 (0.980-1.003)	0.139
Total bilirubin	1.534 (0.604-3.894)	0.368
ALT	1.007 (0.999-1.015)	0.079
ALP	1.001 (0.991-1.012)	0.813
Fasting glucose	1.002 (0.991-1.013)	0.771
CA19-9	1.022 (0.005-1.049)	0.116
HBsAg positivity	2.461 (0.587-10.327)	0.218

¹Right upper quadrant pain, epigastric pain, vague abdominal discomfort, dyspepsia, fatigue, body weight loss. GB: Gallbladder; BMI: Body mass index; ALT: Alanine transaminase; ALP: Alkaline phosphatase; CA19-9: Carbohydrate antigen 19-9; HBsAg: Hepatitis B surface antigen.