Lymphoepithelioma-like cholangiocarcinoma: A mimic of hepatocellular carcinoma on imaging features

Figure 4 Histochemical findings. A: The tumor is well circumscribed with a thick fibrous capsule (HE stain, × 20); B: The majority of the tumor is composed of well differentiated glandular cells with dense lymphocytic infiltration and scattered lymphoid follicles (HE stain, × 200); high-power view of another area in the tumor; C: The tumor reveals a solid, poorly differentiated growth pattern (HE stain, × 200); D: In situ hybridization for Epstein-Barr virus-encoded RNA is diffusely positive in the tumor cells (× 200).