Differentiation of acute and chronic hepatitis B in IgM anti-HBc positive patients

Figure 2 Receiver operating characteristic curves comparing immunoglobulin M antibodies to the hepatitis B core antigen, hepatitis B virus DNA and a combination of immunoglobulin M antibodies to the hepatitis B core antigen and hepatitis B virus DNA in patients with acute hepatitis B vs those with chronic hepatitis B with acute exacerbation. The area under receiver operating characteristic (AUROC) curves for IgM anti-HBc, HBV-DNA and combination are indicated in the inset. P = 0.0056 for HBV DNA vs combination, P = 0.22 for combination vs immunoglobulin M antibodies to the hepatitis B core antigen (IgM anti-HBc).