Oxaliplatin and 5-fluorouracil hepatic infusion with lipiodolized chemoembolization in large hepatocellular carcinoma

Table 3 Univariate and multivariate analysis of predictors of survival of all 132 patients

Characteristic	Univariate	Multivariate	HR	95%CI
Age ( ≤ 65 yr >)	0.53
Gender	0.46
Clip score	0.29
BCLC (B, C)	0.03
ECOG (0, 1, 2)	0.57
Cirrhosis	0.73
Solitary or multiple nodules	0.74
Vascular invasion	0.00	0.00	2.36	1.41-2.94
Extrahepatic spread	0.04	0.34	1.27	0.78-2.10
AFP-pre	0.02
< 20 ng/mL		0.09
20-400 ng/mL		0.19	0.71	0.43-1.20
> 400 ng/mL		0.22	1.41	0.81-2.49
HBV DNA > 104 copies/mL	0.21
Gelatin-sponge application	0.47

AFP-pre: Alpha-fetoprotein at baseline; BCLC: Barcelona Clinic Liver Cancer; CI: Confidence interval; ECOG: Eastern Cooperative Group; HBV: Hepatitis B virus; HR: Hazard ratio.