Oxaliplatin and 5-fluorouracil hepatic infusion with lipiodolized chemoembolization in large hepatocellular carcinoma

Table 2 Univariate and multivariate analysis of predictors of tumor progression of all 132 patients

Characteristic	Univariate	Multivariate	HR	95%CI
Age ( ≤ 65 yr >)	0.84
Gender	0.88
Clip score	0.05
BCLC (B, C)	0.02
ECOG (0, 1, 2)	0.59
Cirrhosis	0.79
Solitary or multiple nodules	0.50
Vascular invasion	0.01	0.30	0.75	0.44-1.29
Extrahepatic spread	0.04	0.26	0.73	0.42-1.27
AFP-pre	0.02
< 20 ng/mL		0.05
20-400 ng/mL		0.04	0.55	0.30-0.99
> 400 ng/mL		0.50	1.23	0.67-2.28
HBV DNA > 104 copies/mL	0.66
Gelatin-sponge application	0.26

AFP-pre: Alpha-fetoprotein at baseline; BCLC: Barcelona Clinic Liver Cancer; CI: Confidence interval; ECOG: Eastern Cooperative Group; HBV: Hepatitis B virus; HR: Hazard ratio.