Methylation of IRAK3 is a novel prognostic marker in hepatocellular carcinoma

doi:10.3748/wjg.v21.i13.3960

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Apr 7, 2015 (publication date) through Jan 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 7, 2015; 21(13): 3960-3969
Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3960

Table 3 Methylation frequency of IRAK3 and GLOXD1 in liver tissues

Symbol	M-Index¹cut-off value	No. of methylated cases/total			P value²
Symbol	M-Index¹cut-off value	Normal controls	Nontumor tissues	HCC tissues	P value²
IRAK3	8.90	1/29 (3.4%)	23/160 (14.4%)	102/160 (63.8%)	< 0.0001
GLOXD1	0.60	2/29 (6.9%)	4/160 (2.5%)	75/160 (46.9%)	< 0.0001

¹Methylation-Index: the best cut-off value to discriminate 29 normal controls and 160 hepatocellular carcinoma (HCC) tissues;

²χ² test for trend.

Citation: Kuo CC, Shih YL, Su HY, Yan MD, Hsieh CB, Liu CY, Huang WT, Yu MH, Lin YW. Methylation of IRAK3 is a novel prognostic marker in hepatocellular carcinoma. World J Gastroenterol 2015; 21(13): 3960-3969
URL: https://www.wjgnet.com/1007-9327/full/v21/i13/3960.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i13.3960