Is endoscopic submucosal dissection safe for papillary adenocarcinoma of the stomach?

Table 3 Predictive factors of lymph node metastasis in papillary adenocarcinoma-type early gastric cancers n (%)

Factors	Lymph node metastasis		P value
	Present(n = 9)	Absent(n = 40)
Location			0.712
Upper third	0 (0)	5 (100)
Middle third	0 (0)	2 (100)
Lower third	9 (21.4)	33 (78.6)
Macroscopic type			0.683
Elevated	6 (16.7)	30 (83.3)
Depressed	3 (23.1)	10 (76.9)
Ulceration			0.498
Absent	6 (16.2)	31 (83.8)
Present	3 (25.0)	9 (75.0)
Histologic type			0.470
PP type	4 (14.3)	24 (85.7)
MP with diff.	2 (16.7)	10 (83.3)
MP with undiff.	3 (33.3)	6 (66.7)
Tumor size			0.253
≤ 30 mm	3 (12.5)	21 (87.5)
> 30 mm	6 (24.0)	19 (76.0)
Depth of invasion			0.195
Mucosa	1 (7.1)	13 (92.9)
Submucosa	8 (22.9)	27 (77.1)
Lymphovascular invasion			0.016
Absent	3 (8.6)	32 (91.4)
Present	6 (42.9)	8 (57.1)

PP type: Pure papillary type; MP + diff.: Mixed papillary type with differentiated component; MP + undiff.: Mixed papillary type with undifferentiated component.