Helicobacter pylori and serum kynurenine-tryptophan ratio in patients with colorectal cancer

Table 2 Comparison of neopterin, tryptophan, kynurenine, nitrite, biopterin levels (mean ± SE) in Helicobacter pylori seronegative controls and Helicobacter pylori seronegative colorectal cancer patients

	H. pylori seronegativecontrol group(n = 37)	H. pylori seronegativecolorectal cancer group (n = 19)	P value
Serum neopterin (nmol/L)	8.10 ± 1.11	20.89 ± 6.27	0.010a
Tryptophan (nmol/L)	20.37 ± 0.89	15.71 ± 1.16	0.003a
Kynurenine (nmol/L)	0.89 ± 0.12	1.22 ± 0.18	0.007a
Kynurenine/tryptophan (mmol/mmol)	52.85 ± 11.85	78.91 ± 8.68	0.000a
Nitrite (mmol/L)	21.86 ± 1.81	25.51 ± 4.34	0.938
Urinary biopterin/creatinine (mmol/mol)	116.20 ± 12.87	119.1 ± 11.6	0.573

^aP < 0.05, Helicobacter pylori (H. pylori) seronegative control vs H. pylori seronegative cancer patients.