Thiopurine metabolites variations during co-treatment with aminosalicylates for inflammatory bowel disease: Effect of N-acetyl transferase polymorphisms

Table 1 Genotypes and methods of analysis considered in this study

Gene	Polymorphism	Method	References
NAT1	T1088A	Sequencing	With primer forward: 5’-TGCCCAAACATGGTGATAGATTT-3’
			With primer reverse: 5’-CCATAAAACTTTTCTAGGAATTCAACAAT-3’
NAT1	C1095A	Sequencing	As above
NAT2	C282T	PCR-RFLP	[23,24]
NAT2	T341C	PCR-RFLP	[23,24]
TPMT	G238C	PCR-ASO	[27]
TPMT	G460A	PCR-RFLP	[27]
TPMT	A719G	PCR-RFLP	[27]
ITPA	C94A	TaqMan	TaqMan SNP genotyping assay from
			Applied biosystems (C_27465000_10)