MicroRNA-1290 promotes esophageal squamous cell carcinoma cell proliferation and metastasis

Figure 5 miR-1290 negatively regulates the mRNA and protein expression of suppressor of cancer cell invasion. A: mRNA expression of SCAI in Eca109 cells transfected with miR-1290 mimic decreased evidently compared with that in cells transfected with miR-1290 nc. Conversely, the mRNA expression of SCAI in TE13 cells transfected with miR-1290 inhibitor increased evidently compared with that in cells transfected with miR-1290 inc; B: Protein expression of SCAI exhibited a similar pattern in Eca109 cells transfected with miR-1290 mimic and miR-1290 nc or in TE13 cells transfected with miR-1290 inhibitor and miR-1290 inc. ^bP < 0.01 vs control. nc: Negative control; inhi: Inhibitor; inc: Inhibitor negative control; SCAI: Suppressor of cancer cell invasion.