Retrospective Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Mar 21, 2015; 21(11): 3308-3316
Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3308
Table 4 Univariate analysis of risk factors for active tuberculosis infection after anti-TNF therapy n (%)
TB infection + (n = 16)TB infection - (n = 360)P value
Age at anti-TNF (yr)26 (21-70)30 (11-76)0.808
Female3 (18.8)118 (32.8)0.287
Diseases0.772
Crohn’s disease11 (68.8)266 (73.9)
Ulcerative colitis5 (31.3)94 (26.1)
Diabetes mellitus1 (6.3)11 (3.1)0.411
Anti-TNF agent0.212
Infliximab15 (93.8)279 (77.5)
Adalimumab1 (6.3)81 (22.5)
LTBI4 (25)26 (7.2)0.031
IM at anti-TNF agent13 (81.3)228 (63.3)0.187
WBC count < 5000 mm310 (62.5)115 (31.9)0.015