Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways

Figure 7 Expression of negative regulators of TLR signaling. A: Expression of Toll-interacting protein (Tollip), interleukin-1R-associated kinase (IRAK-M), suppressor of cytokine signaling (SOCS)-1 and Src homology 2 domain-containing inositol-5-phosphatase (SHIP-1) in liver at 6 h after reperfusion were evaluated by Western blotting assay using whole cell lysates; B: Results was quantified and expressed by the ratio to β-actin. Mean ± SE are shown (n = 4/group). I/R: Ischemia/reperfusion; CoPP: Cobalt protoporphyrin; ZnPP: Zinc protoporphyrin.