Nonselective beta-blockers in cirrhotic patients with no or small varices: A meta-analysis

Table 4 Results of subgroup analyses

Category	Studies,	Patients,	OR (95%CI)	Heterogeneity	Subgroup difference
	n	n
Development of large varices
No varices	2	292	2.43 (0.44-13.55)	I² = 71%	I² = 0%
			P = 0.31	P = 0.06	P = 0.51
Small varices	3	444	1.07 (0.19-6.18)	I² = 93%
			P = 0.94	P < 0.01
First bleeding
No varices	1	213	0.38 (0.07-1.99)	NA	I² = 0%
			P = 0.25		P = 0.64
Small varices	4	398	0.64 (0.15-2.79)	I² = 47%
			P = 0.55	P = 0.13
Death
No varices	1	213	0.61 (0.26-1.43)	NA	I² = 0
			P = 0.26		P = 0.84
Small varices	2	311	0.68 (0.37-1.26)	I² = 0%
			P = 0.22	P = 0.39
Adverse events
No varices	1	213	1.94 (1.11-3.38)	NA	I² = 37.1%
			P = 0.02		P = 0.21
Small varices	2	311	5.75 (1.17-28.29)	I² = 15%
			P = 0.03	P = 0.28

NA: Not assessed; OR: Odds ratio.