Corticosteroid therapy in ulcerative colitis: Clinical response and predictors

Table 4 Logistic regression analysis of risk factors for corticosteroid dependence at one month after start of corticosteroid

	P value1		OR (95%CI)
	Univariate	Multivariate
Sutherland score (≥ 6)	0.037	0.014	2.347 (0.935-5.890)
Abnormal neutrophil%	0.016	0.107	0.425 (0.168-1.075)
Weight loss	0.021	0.336	2.400 (0.839-6.866)
Mucus	0.096
Diarrhea (> 6/d)	0.136
Hypokalemic (< 3.5 mmol/L)	0.176
ESR (> 15 mm/h)	0.186
Bloody stool	0.343

¹Data with univariate P < 0.5 are not displayed. All the variables were statistically analyzed. In univariate analysis, Sutherland score (≥ 6), abnormal neutrophil% and weight loss after one month of corticosteroid treatment were related with corticosteroid dependence (P = 0.037, 0.016, 0.021). All the variables with P < 0.100 were further analyzed by logistic regression. After multivariate analysis, sustained high Sutherland score (≥ 6) after one-month treatment was found to be associated with corticosteroid dependence (OR = 2.347; 95%CI: 0.935-5.890; P = 0.014).