Corticosteroid therapy in ulcerative colitis: Clinical response and predictors

Table 2 Logistic regression analysis of risk factors for corticosteroid dependence before start of corticosteroid

	P value1		OR (95%CI)
	Univariate	Multivariate
Tenesmus	0.012	0.013	0.336 (0.147-0.768)
Anemia	0.041	0.338	0.576 (0.233-1.422)
Hypokalemic (< 3.0 mmol/L)	0.065	0.060	0.121 (0.014-1.028)
Diarrhea (> 6/d)	0.135
ESR (> 15 mm/h)	0.193
Weight loss	0.260
Tachycardia (≥ 90/min)	0.280
Hypoproteinemia (< 3.5 mg/dL)	0.373

¹Data with univariate P < 0.5 are not displayed. All the variables were statistically analyzed. In univariate analysis, tenesmus and anemia before start of corticosteroid treatment were related with corticosteroid dependence (P = 0.012, 0.041). All the variables with P < 0.100 were further analyzed by logistic regression. After multivariate analysis, tenesmus at baseline was found to be associated with corticosteroid dependence (OR = 0.336, 95%CI: 0.147-0.768; P = 0.013). ESR: Erythrocyte sediment rate.