Clinical outcome of medium-sized hepatocellular carcinoma treated with microwave ablation

Table 3 Cox survival analysis of predictors for overall survival in 182 patients with hepatocellular carcinoma following microwave ablation

	Univariate			Multivariate
	HR	95%CI	Pvalue	HR	95%CI	Pvalue
Tumor diameter	1.314	0.692-2.439	0.404
Sex (male/female)	1.403	0.537-3.667	0.490
Age (> 60 yr/ ≤ 60 yr)	0.912	0.444-1.871	0.801
Child-Pugh classification (A/B)	0.492	0.149-1.622	0.244
ALB (> 35 g/L/ ≤ 35 g/L)	5.969	2.938-12.129	0.000	3.296	1.340-8.111	0.009
ALT (> 41 U/L, ≤ 41 U/L)	0.921	0.454-1.868	0.819
Total bilirubin (> 34.2 mmol/L/18.8-34.2 mmol/L/ ≤ 18.8 mmol/L)	0.488	0.306-0.778	0.003	0.881	0.528-1.469	0.626
AFP(> 400 mg/L/20-400 mg/L/ ≤ 20 mg/L)	0.657	0.433-0.998	0.049	0.834	0.533-1.305	0.427
Etiology of HCC [HBV/HCV/HBV + HCV/Other reason(s)]	0.910	0.658-1.258	0.566
PLT (≥ 100 × 109/L/45 × 109-100 × 109/L/＜ 45 × 109/L)	2.040	1.277-3.259	0.003	1.148	0.451-2.924	0.772
Portal hypertension (Yes/No)	0.327	0.154-0.695	0.004	0.802	0.188-3.413	0.765
Local tumor recurrence(s) (Yes/No)	0.543	0.190-1.553	0.255
New lesion(s) (Yes/No)	3.678	1.688-8.017	0.001	2.517	1.098-5.771	0.029

PLT: Platelet; ALB: Albumin; ALT: Alanine aminotransferase; AFP: Alpha-fetoprotein; HBV: Hepatic B virus; HCV: Hepatic C virus; HCC: Hepatocellular carcinoma.