Enterocyte dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin expression in inflammatory bowel disease

Figure 5 T lymphocyte differentiation and proliferation induced by mouse intestinal epithelial cells. A: Flow cytometric analysis of interferon (IFN)-γ and interleukin (IL)-4 levels in CD4⁺ T cells; B: Enzyme-linked immunosorbent assay of IFN-γ and IL-4 levels in co-culture supernatants; C: Flow cytometric analysis of T cell proliferation (0, undivided cells; 1, generation 1; 2, generation 2; 3, generation 3; 4, generation 4; 5, generation 5). a: Control group, b: Dextran sodium sulfate-treated group, c: Anti-P-selectin lectin-EGF domain monoclonal antibody-treated group; ^aP < 0.05 vs controls; ^cP < 0.05 vs dextran sodium sulfate-treated group. No significant changes in IFN-γ groups.