Concomitant therapy achieved the best eradication rate for Helicobacter pylori among various treatment strategies

Table 2 First-line eradication rates of Helicobacter pylori

	Achieved/analyzed patients (n)	Eradication rate, (95%CI)	P value1	P value2
Per protocol			0.001
PAC (n = 143)	109/143	76.2% (69.3-83.2)		< 0.001
PAM (n = 139)	117/139	84.2% (78.1-90.2)		0.016
Sequential (n = 141)	119/141	84.4% (78.4-90.4)		0.018
Concomitant (n = 143)	135/143	94.4% (90.6-98.2)		-
Intent-to-treat			0.001
PAC (n = 170)	109/170	64.1% (58.8-73.0)		0.007
PAM (n = 170)	117/170	68.8% (66.3-79.2)		0.285
Sequential (n = 170)	119/170	70.7% (65.0-78.5)		0.169
Concomitant (n = 170)	135/170	79.4% (74.6-86.5)		-

¹P-value of χ² test;

²Bonferroni adjusted P-value of χ² test on 2 × 2 subtables. PAC: Rabeprazole, amoxicillin and clarithromycin; PAM: Rabeprazole, amoxicillin and metronidazole.