Autoantibodies in Chinese patients with chronic hepatitis B: Prevalence and clinical associations

Table 5 Anti-nuclear antibodies fluorescence patterns and cirrhosis in chronic hepatitis B: Comparison of the non-cirrhosis, compensated cirrhosis and decompensated cirrhosis groups n (%)

	Non-cirrhosis1 (n = 117)		Compensated cirrhosis (n = 85)		Decompensated cirrhosis2 (n = 119)
	Pos.	P value	Pos.	P value	Pos.	P value
ANA-H	32 (27.4)	0.001	7 (8.2)	< 0.001	8 (6.7)	0.683
ANA-DM	1 (0.9)	0.403	3 (3.5)	0.223	5 (4.2)	1.000
ANA-other3	4 (3.4)	0.396	6 (7.1)	0.767	6 (5.0)	0.546

¹Two cases showed the combination of ANA-H/ANA-DM and ANA-DM/ANA-other fluorescence patterns, thus these two cases were excluded from this group;

²Two cases showed the combination of ANA-H/ANA-Others and ANA-DM/ANA-other fluorescence patterns, thus these two cases were excluded from this group;

³Fluorescence patterns such as centromeres, nuclear speckles, and nucleoli were included. P < 0.05, non-cirrhosis vs compensated cirrhosis, non-cirrhosis vs decompensated cirrhosis, and compensated vs decompensated cirrhosis, respectively, was considered significant. ANA: Anti-nuclear antibodies; ANA-H: ANA-homogeneous; ANA-DM: ANA-dots or membrane.