Clinical outcomes of small cell neuroendocrine carcinoma and adenocarcinoma of the gallbladder

Table 4 Small cell neuroendocrine carcinoma of the gallbladder of the literature

Ref.	Age(yr)	Sex	Size (cm)	Meta or local inv	Mixed tumor	Survival (mo)	Tumor stage	Chromogranin A	Recurrence (site)	Operation type
Moskal et al[22], 1999	69	F	NA	Regional LN meta, pancreas inv	+	44	T3	NA	+ (abdomen)	Radical
	57	F	NA	Regional LN meta, liver inv	-	31	T3	NA	+ (abdomen, bone)	Radical
	69	M	NA	Regional LN meta	-	21	T2	NA	+ (retroperitoneum)	C
	71	F	NA	Regional LN meta peritoneum meta	+	13	T2	NA	+ (retroperitoneum)	C
	40	M	NA	Regional LN meta	+	189, alive	T2	NA	+ (lung, abdomen)	C
Maitra et al[21], 2001	85	F	4.0	Liver meta	+	13	≥ T2	+	NA	Surg
	77	F	2.8	Pancreas inv, LN meta	+	25	≥ T2	NA	NA	Surg
	43	F	2.0	Liver meta	+	9	≥ T2	+	NA	Surg
	73	F	2.5	LN meta	+	7	≥ T2	+	NA	Surg
	82	M	1.0	Liver meta	+	8	≥ T2	NA	NA	Surg
	77	F	3.0	-	+	10	≥ T2	+	NA	Surg
	73	M	6.3	Liver meta	-	6	≥ T2	NA	NA	Surg
	71	M	NA	-	-	3	T1	NA	NA	Surg
	37	F	8.0	LN meta	-	7	≥ T2	NA	NA	Surg
	68	M	2.0	LN meta	-	14	≥ T2	+	NA	Surg
	67	F	2.8	-	-	NA	≥ T2	+	NA	Surg
	78	M	1.8	LN meta	-	16	≥ T2	NA	NA	Surg
Lane et al[11], 2002	67	M	NA	-	-	11	T1b	+	+ (liver, LN)	C
Iype et al[16], 2008	32	F	2.0	Regional LN meta, liver meta	-	14, alive	T2	+	+ (liver, LN)	Radical
Current study, 2014	49	F	1.9	-	-	37, alive	T2	+	-	Radical
	66	M	1.5	Regional LN meta	+	13, alive	T2	+	-	Radical
	63	F	3.0	-	-	67, died	T2	-	+ (liver)	C
	45	F	9.5	LN inv, colon inv, liver inv	+	50, alive	T3	-	-	Radical

C: Cholecystectomy; F: Female; inv: Invasion; LN: Lymph node; M: Male; meta: Metastasis; NA: Not available; Surg: Extent of surgery not reported.