Clinical outcomes of small cell neuroendocrine carcinoma and adenocarcinoma of the gallbladder

Table 2 Clinicopathologic features

Characteristic	GB-adenocarcinoma(n = 38)	GB-NEC-SCC(n = 4)	P value
Sex			1.000
Male	15	1
female	23	3
Age, yr	67.89 ± 11.15	55.75 ± 10.31	0.029
Age groups, n			0.080
< 65 yr	10	3
≥ 65 yr	28	1
Operation type, n			1.000
Simple cholecystectomy	10	1
Extended cholecystectomy	28	3
Tumor size, cm	2.56 ± 1.75	3.98 ± 3.74	0.788
Tumor size groups, n			0.609
< 2 cm	11	2
≥ 2 cm	21	2
Tumor stage, n			0.410
T2	34	3
T3	4	1
Lymphovascular invasion, n			0.245
-	29	2
+	8	2
Perineural invasion, n			0.107
-	26	1
+	11	3
Lymph node metastasis, n			0.537
-	18	1
+	9	2
Lymph node ratio	0.15 ± 0.29	0.18 ± 0.28	0.485
Recurrence, n			1.000
-	28	3
+	10	1

GB: Gallbladder; GB-NEC-SCC: Small cell neuroendocrine carcinoma of the gallbladder.