Long-term survival after resection of pancreatic cancer: A single-center retrospective analysis

Table 4 Clinicopathological characteristics of 5-year survivors and non-survivors

Variables	5-yr survivors(n = 20)	Non-survivors(n = 76)	P value
Age (mean ± SD)	65.5 ± 9.4	67.2 ± 7.9	0.393
Gender			0.398
Male	10	46
Female	10	30
Tumor marker, median (IQR)
CEA (ng/mL)	2.0 (1.3-2.7)	3.0 (1.6-5.4)	0.536
CA19-9 (U/mL)	57.0 (35.0-378.0)	213.5 (48.0-594.5)	0.071
DUPAN-2 (U/mL)	79.5 (25.0-508.0)	312.5 (55.8-965.3)	0.032a
Tumor size			0.008a
> 20 mm, n	13	70
≤ 20 mm, n	7	6
UICC T classification			0.161
T1, n	1	1
T2, n	0	3
T3, n	19	66
T4, n	0	6
Surgical margin status			0.004a
R0, n	19	46
R1, n	1	26
R2, n	0	4
Lymph node metastasis			0.036a
Positive, n	8	62
Negative, n	12	14
Extrapancreatic neural invasion			0.200
Positive	10	50
Negative	10	26
Portal invasion			0.005a
Positive	2	31
Negative	18	45
UICC stage			0.184
IA, n	1	1
IB, n	0	1
IIA, n	7	11
IIB, n	10	43
III, n	0	4
IV, n	2	16
Adjuvant chemotherapy			0.707
Yes	15	60
No	5	16
Time to initiation of adjuvant chemotherapy (d)	36.0 ± 24.0	64.5 ± 83.1	0.107

CEA: Carcinoembryonic antigen; UICC: Union for international cancer control.

^aP < 0.05.