Azathioprine is essential following cyclosporine for patients with steroid-refractory ulcerative colitis

Table 3 Clinical data and outcome of responders to CyA therapy

					Endoscopic findings1			Clinical factors1
Case No.	Age	Sex	Duration of UC	Disease extent	Poor extensibility	Deep ulcer	Mucosal bleeding	CAI	CRP	Hgb	Outcome
1	23	F	24M	Pancolitis	(-)	(+)	(-)	17	3.2	9.3	Operation at 4M
2	37	M	67M	Pancolitis	(-)	(+)	(+)	16	1.5	10.9	No operation
3	23	M	44M	Pancolitis	(-)	(+)	(-)	15	7.0	13.7	Operation at 1Y, 4M
4	32	F	77M	Pancolitis	(-)	(-)	(-)	14	1.3	8.6	Operation at 2Y, 10M
5	31	F	26M	Pancolitis	(-)	(-)	(-)	13	12.8	13.4	No operation
6	9	F	13M	Pancolitis	(-)	(-)	(-)	15	12.5	13.2	Operation at 5M
7	16	M	79M	Lt-sided colitis	(-)	(+)	(-)	15	12.8	11.9	Operation at 1M
8	16	F	1M	Pancolitis	(-)	(+)	(-)	17	8.1	8.7	No operation
9	31	M	65M	Lt-sided colitis	(-)	(+)	(-)	12	14.7	10.0	No operation
10	21	M	22M	Pancolitis	(-)	(+)	(-)	17	6.4	11.8	No operation
11	49	M	27M	Lt-sided colitis	(+)	(+)	(+)	13	13.7	7.8	No operation
12	29	F	47M	Pancolitis	(+)	(+)	(+)	13	4.6	8.0	No operation
13	61	M	9M	Pancolitis	(+)	(+)	(-)	15	0.4	10.7	No operation
14	54	M	300M	Pancolitis	(+)	(+)	(+)	12	7.1	13.5	No operation
15	26	M	134M	Pancolitis	(+)	(+)	(+)	18	4.1	10.9	Operation at 2M

¹At beginning of cyclosporine treatment; M: Months; Y: Years. CAI: Clinical activity index; CRP: C-reactive protein; UC: Ulcerative colitis.