Beneficial effect of an omega-6 PUFA-rich diet in non-steroidal anti-inflammatory drug-induced mucosal damage in the murine small intestine

doi:10.3748/wjg.v21.i1.177

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 7, 2015; 21(1): 177-186
Published online Jan 7, 2015. doi: 10.3748/wjg.v21.i1.177

Table 4 Effect of dietary fat treatment on the area of small intestinal lesions induced by indomethacin¹

Lipid	Diet
Lipid	R	BT	FO	SO
Without IND (mm²)	0.80 ± 0.11	0.9 ± 0.13	0.7 ± 0.11	0.70 ± 0.14
With IND (mm²)	21.8 ± 2.3	32.1 ± 3.2^a^b	41.6 ± 3.1^a^b	19.1 ± 1.70

¹Values are represented as mean ± SEM, n = 8-12;

^aP < 0.05 vs IND,

^bP < 0.05 vs IND + SO. IND: Indomethacin; R: Reference diet (CE-2); BT: Beef tallow; FO: Fish oil; SO: Safflower oil.

Citation: Ueda T, Hokari R, Higashiyama M, Yasutake Y, Maruta K, Kurihara C, Tomita K, Komoto S, Okada Y, Watanabe C, Usui S, Nagao S, Miura S. Beneficial effect of an omega-6 PUFA-rich diet in non-steroidal anti-inflammatory drug-induced mucosal damage in the murine small intestine. World J Gastroenterol 2015; 21(1): 177-186
URL: https://www.wjgnet.com/1007-9327/full/v21/i1/177.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i1.177