Copyright
©The Author(s) 2015.
World J Gastroenterol. Jan 7, 2015; 21(1): 132-138
Published online Jan 7, 2015. doi: 10.3748/wjg.v21.i1.132
Published online Jan 7, 2015. doi: 10.3748/wjg.v21.i1.132
Table 1 Variables confounding the association between nodal count and survival in colorectal cancer
Confounding variables | Effect on LNC | |
Patient characteristics | ↑Age, ↓socioeconomic status, non-Caucasian race | ↓ |
gender, body mass index | ? | |
Tumor characteristics | ↑Tumor diameter, T stage, overall cancer stage, lymphocytic infiltration, MSI-H phenotype | ↑ |
↑Tumor grade | ↓ | |
Mucinous differentiation, lymphovascular and perineural invasion | ? | |
Surgical factors | Open vs minimally invasive resection | None |
Colorectal vs general surgeons, advanced fellowship training | ↑ | |
Surgeon volume | ? | |
Institutional factors | High-volume centers, teaching hospitals, significant CC surgical practice, academic pathology laboratories | ↑ |
Preoperative radiochemotherapy for rectal cancer | ↓ | |
Factors related to pathology examination | Xylene/alcohol fat clearance, embedding of the entire mesentery vs traditional dissection, ex vivo intra-arterial methylene blue injection, tattooing of neoplasms during colonoscopy, pathologists interested in CRC, use of a standardized protocol to evaluate CC specimens | ↑ |
- Citation: Willaert W, Ceelen W. Extent of surgery in cancer of the colon: Is more better? World J Gastroenterol 2015; 21(1): 132-138
- URL: https://www.wjgnet.com/1007-9327/full/v21/i1/132.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i1.132