Optimum chemotherapy in the management of metastatic pancreatic cancer

doi:10.3748/wjg.v20.i9.2352

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2014; 20(9): 2352-2357
Published online Mar 7, 2014. doi: 10.3748/wjg.v20.i9.2352

Table 2 The approved chemotherapeutical regimens for metastatic pancreatic cancer in patients with good performance status

Ref.	Regimen	ORR	Median OS (mo)	Median PFS (mo)
Burris et al[2]	Gemcitabine	ND	5.65	2.33
Burris et al[2]	5-FU	ND	4.41	0.92
Conroy et al[3]	FOLFIRINOX	31.6%	11.1	6.4
Conroy et al[3]	Gemcitabine	9.4%	6.8	3.3
Moore et al[12]	Gemcitabine/erlotinib	8.6%	6.24	3.75
Moore et al[12]	Gemcitabine	8.0%	5.91	3.55
Daniel et al[20]	Gemcitabine/nab-paclitaxel	23%	8.5	5.5
Daniel et al[20]	Gemcitabine	7%	6.7	3.7

ORR: Objective response rate; OS: Overall survival; PFS: Progression free survival; ND: Not determined.

Citation: Ghosn M, Kourie HR, Karak FE, Hanna C, Antoun J, Nasr D. Optimum chemotherapy in the management of metastatic pancreatic cancer. World J Gastroenterol 2014; 20(9): 2352-2357
URL: https://www.wjgnet.com/1007-9327/full/v20/i9/2352.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i9.2352