Management of borderline and locally advanced pancreatic cancer: Where do we stand?

doi:10.3748/wjg.v20.i9.2255

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2014; 20(9): 2255-2266
Published online Mar 7, 2014. doi: 10.3748/wjg.v20.i9.2255

Table 2 Summary of recent chemotherapy trials for locally advanced pancreatic cancer

CHEMO trials	Component	Median survival	P value
GERCORD/GISCAD[66]	Gem ± oxaliplatin	9.0 mo vs 7.1 mo	0.13
Van Cutsem et al[67]	Gem ± tipifarnib	193 d vs 182 d	0.75
IRINOGEM[68]	Gem ± irinotecan	6.3 mo vs 6.6 mo	0.79
Von Hoff et al[69]	Gem ±nab-paclitaxel	8.5 mo vs 6.7 mo	< 0.001
PRODIGE[70]	Gem vs FOLFIRINOX	6.8 mo vs 11.1 mo	< 0.001

CHEMO: Chemotherapy; Gem: Gemcitabine.

Citation: He J, Page AJ, Weiss M, Wolfgang CL, Herman JM, Pawlik TM. Management of borderline and locally advanced pancreatic cancer: Where do we stand? World J Gastroenterol 2014; 20(9): 2255-2266
URL: https://www.wjgnet.com/1007-9327/full/v20/i9/2255.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i9.2255