Targeted therapy in gastric cancer: Personalizing cancer treatment based on patient genome

Figure 3 Simple scoring analysis of Asian gastric cancer. Three criteria were used to select key genes: (1) Genes that were identified in both 5-group and 4-stage differential expression analysis; (2) Target genes of six key differentially expressed miRNAs, where the target genes were predicted by TargetScan (Rs < -0.4, P < 0.05); and (3) Genes with recurrent somatic mutations or their interactors (Ingenuity Pathway Analysis program annotation). Only two genes met two criteria, and PRKAA2 was the only gene that met all three criteria. miRNA: MicroRNA.