Sophocarpine attenuates liver fibrosis by inhibiting the TLR4 signaling pathway in rats

Figure 5 Sophocarpine suppresses the proliferation of hepatic stellate cells. A: Activated HSCs were treated with a gradient concentration of sophocarpine and the proliferation of HSCs was assessed using the CCK-8 kit; B: Real-time polymerase chain reaction was performed to examine the expression of Cyclin D1 in HSCs after treatment with a gradient concentration of sophocarpine (^aP < 0.05); C: Western blot was employed to detect PCNA expressed in HSCs after treatment with sophocarpine. HSCs: Hepatic stellate cells; PCNA: Proliferating cell nuclear antigen.