Diet high in fructose leads to an overexpression of lipocalin-2 in rat fatty liver

Figure 7 Representative photomicrographs show immunolocalization of key markers of Neutrophil granulocytes infiltration. Myeloperoxidase (MPO) double-stained with LCN-2 (left-panel), and tissue macrophages (ED1) plus LCN-2 (right-panel) at week 4; A co-localization of LCN-2 and MPO can be detected in liver sections. The black cavities (vesicles) that were marked by Star in L-HFr micrographs resulted from washing of fat from hepatocytes during fixation step. Red arrows in right panel show ED1⁺ cells. Scale bar = 200 μm. Co: Chow diet, LDC: Lieber-DeCarli liquid diet; L-HFr: LDC + 70% fructose.