Diet high in fructose leads to an overexpression of lipocalin-2 in rat fatty liver

Figure 3 Alterations in hepatic mRNA levels of inflammation- and metabolism-related genes. A-C: Bar plots show relative specific mRNA levels of inflammation-related mediators in hepatic specimens that were up-regulated in the L-HFr group at both time points; D-F: Only increased at 4^th week; G-H: Selected metabolism-related genes; Each bar represents mean ± SEM of 4 rats/group at weeks 4 and 8; Data were normalized by Ubc (ubiquitin C), and Actb (β-actin) was additionally used as a reference housekeeping gene. ^bP < 0.001. Co: Chow pellets; LDC: Lieber-DeCarli liquid diet; L-HFr: LDC combined with 70% fructose.