Regulation of hepatic EAAT-2 glutamate transporter expression in human liver cholestasis

Figure 7 EAAT2 transporter expression in human cholestatic liver tissue. A: In non cholestatic liver disease, some rare hepatocytes show membranous staining; B: In PFIC type 2, this expression increased, but was still limited to some hepatocytes. In the case of biliary atresia (C) and progressive familial intrahepatic cholestasis (PFIC) type 3 (D), the membrane expression is strong and observed in numerous hepatocytes (original magnification × 200).