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Copyright ©2014 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 14, 2014; 20(6): 1402-1423
Published online Feb 14, 2014. doi: 10.3748/wjg.v20.i6.1402
Table 1 Proteins that have been experimentally identified as secreted in one of the reported papers or predicted based on a secretion signal
LabelName and/or functionRef.PDB codeUniProtKB
Outer membrane proteins (Omps)
HP0009Outer membrane protein (Omp1), HopZyQ7X2J7
HP0025Outer membrane protein (Omp2)b’, yO24870
HP0078/79Outer membrane protein (Omp3)yO24907/O24908
HP0127Outer membrane protein (omp4), HorBb’, y, zO24941
HP0227Outer membrane protein (Omp5)b’, yO34523
HP0229Outer membrane protein (Omp6)b’, y, zO25015
HP0232UPF0323 lipoprotein HP_0232bO25018
HP0252Outer membrane protein (Omp7), HopFb’, yO25034
HP0253Outer membrane protein (Omp8)yO25035
HP0317Outer membrane protein (Omp9)b’, yO25086
HP0324Outer membrane protein (Omp10)yO25091
HP0410Putative neuraminyllactose-binding hemagglutininzO25166
HP0472Outer membrane protein (Omp11)b’, y, zO25218
HP0477Outer membrane protein (Omp12)yO25222
HP0486Putative outer membrane protein, HofCb’, yO25230
HP0487Putative outer membrane protein, HofDb’O25231
HP0638Outer membrane protein (Omp13)yO25355
HP0671Outer membrane protein (Omp14)b’, yO25382
HP0694Putative outer membrane proteinb’, yO25401
HP0706Outer membrane protein (Omp15)b’, zO25410
HP0710Outer membrane protein (HomA)zO25414
HP0722Outer membrane protein (Omp16)y
HP0725Outer membrane protein (Omp17)yQ7X2J9
HP0797Neuraminyllactose-binding hemagglutinin, HpaAb, y3BGHP55969
HP0896Outer membrane protein (Omp19). BabBb’, yO25556
HP0912Outer membrane protein (omp20), AlpAq, u, b’, y, zO25570
HP0913Outer membrane protein (omp21)q, u, b’, yO25571
HP0923Outer membrane protein (Omp22)yO25580
HP1107Outer membrane protein (Omp23)b’, yO25735
HP1125Outer membrane protein (Omp18), peptidoglycan-associated lipoprotein, PALs, yO25625
HP1156Outer membrane protein (Omp25)yO25771
HP1157Outer membrane protein (Omp26)yO25772
HP1177Outer membrane protein (Omp27), HopOb’, yO25791
HP1243Outer membrane protein (Omp28) BabAb’, yO25840
HP1342Outer membrane protein (Omp29)b’, yO34523
HP1395Outer membrane protein (Omp30)y, zO25945
HP1456Lpp20 lipoproteinb, y, zP0A0V0
HP1469Outer membrane protein (Omp31)b’, yO26005
HP1501Outer membrane protein, HopWy, zO26031
HP1512Iron regulated outer membrane proteinyO26042
HP1564Outer membrane protein, lipoproteinu, yO26084
HP1571RlpA-like lipoproteinb, yO26091
HP0284Mechanosensitive ion channel membrane proteinb’O25059
Cag proteins
HP0528CagX, Cag8b’O25263
HP0529CagW, Cag9b’O25264
HP0532CagT, Cag12bP97245
HP0537CagM, Cag16b’O25270
HP0540CagI, Cag19b’O25273
HP0545CagDz3CWX, 3CWYO25277
HP0546Cag25b’O25278
HP0547CagA, Cag26b’, y4G0H, 4DVY, 4DVZ, 3IECP55980
Flagellar components
HP0115Flagellin B, FlaByQ07911
HP0126Flagellar P-ring protein, FlgLbO25028
HP0295Flagellar hook-associated protein 3, HAP3yO25068
HP0325Flagellar L-ring proteinbO25092
HP0601Flagellin A, FlaAv, yP0A0S1
HP0752Flagellar hook-associated protein 2, HAP2zP96786
HP0870Flagellar hook protein FlgEa, yP50610
HP0907Hook flagella assembly protein FlgDa, qO25565
HP1119Flagellar hook-associated protein 1, HAP1yO25744
HP1462Secreted protein involved in flagellar motilityyO25998
HP1557Flagellar hook-basal body protein FliEaP67708
Binding or transport proteins
HP0243Neutophil-activating protein, HP-NAPy, z1JI4, 4EVB, 4EVC, 4EVD, 4EVE, 3T9J, 3TA8P43313
HP0298Periplasmic dipeptide-binding protein, DppAzO25069
HP0508Plasminogen-binding protein pgbAb’O25249
HP0888/Iron (III) dicitrate ABC transporter, ATP-binding proteinvO05732
HP0889
HP0970Nickel-cobalt-cadmium import protein (NccB)b’O25623
HP1073Copper-binding protein, CopPz1YG0Q48271
HP1252Oligopeptide ABC transporter periplasmic oligopeptide-binding protein (OppA)b’O25845
HP1286YceI-like acidic stress response, lipocalina, e, l, u, b’, z3HPEO25873
HP1561/ABC transporter periplasmic binding protein (CeuE)b’O26083/
HP1562O26082
VacA and other toxins
HP0289VacA-like protein, ImaAdO25063
HP0609/HP0610VacA-like protein, FaaAdO25330/
O25531
HP0887Vacuolating cytotoxin VacAa, b, g, u, z2QV3P55981
HP0922VacA-like protein, VlpCdO25579
HP0596Tumor necrosis factor α-inducing protein, Tip-αf, m, n3VNC, 3GUQ, 3GIO, 2WCQ, 2WCRO25318
Enzymes
Redox systems and the electron transport chain
HP0224Peptide methionine sulfoxide reductase MsrA/MsrBb’O25011
HP0231Disulphide interchange protein (DsbG, or DscB or HpDsbA)a, q, u3TDGO25017
HP0330Ketol-acid reductoisomerase, IlvCzO25097
HP0377Thiol-disulfide interchange protein DsbCa, b’4FYB, 4FYCO25140
HP0389Superoxide dismutase, SODx3CEIP43312
HP0390Adhesin-thiol peroxidase, TagDyO25151
HP0485Catalase-like proteinb’O25229
HP0824Thioredoxin TrxAa, wP66928
HP0825Thioredoxin reductase, trxBb’3ISH, 2Q0K, 2Q0LP56431
HP0875Catalase, katAx, b’,z2IQF, 2A9E, 1QWL, 1QWMP77872
HP1136ATP synthase subunit bb’P56086
HP1161Flavodoxin FldAa2W5U, 2BMV, 1FUEO25776
HP1212ATP synthase subunit cb’P56087
HP1227Cytochrome c-553bO25825
HP1266NADH-ubiquinone oxidoreductase, NQO3 subunitzO25856
HP1458Thioredoxin TrxCa, u, zO25996
HP1461Cytochrome c551 peroxidaseb’O25997
Putative solenoid proteins
HP0160Beta-lactamase HcpDb, o, pO24968
HP0211Beta-lactamase HcpA, Cysteine-rich 28 kDa proteinb, o, p, b’O25001
HP0235Beta-lactamase HcpEb, o, p, b’O25021
HP0336Beta-lactamase HcpBo1KLXO25103
HP1098Beta-lactamase, Cysteine-rich protein C HcpCa, b, o, q, t, b’, z1OUVO25728
HP0519Hypothetical Sel1-like proteinpQ7X5D6
HP0628Hypothetical Sel1-like proteinpO25345
HP1117Hypothetical Sel1-like protein, Cys-rich protein XpO25742
HP1124Tetratricopeptide-like repeat proteinb’O25749
Proteases
HP0570Aminopeptidase, PepAzO25294
HP0657Processing protease (YmxG)b’, zO25371
HP1012Putative Zinc proteasezO25656
HP1018/HP1019Serine protease (HtrA)a, f, q, r, zO25663
HP1037Amino peptidaseb’O25681
HP1350Carboxyl-terminal proteasezO25905
Other enzymes
HP0026Citrate synthasezP56062
HP0072Urease B (UreB)a, q, v, y1E9Y, 1E9ZP69996
HP0073Urease A (UreA)y1E9Y, 1E9ZP14916
HP0154Enolase, phosphopyruvate hydratase, enozP48285
HP0194Triosephosphate isomerase, tpiAb’2JGQP56076
HP0275ATP-dependent nuclease (addB)b’, zO25025
HP0294Aliphatic amidase, AimEzO25067
HP0310Polysaccharide deacetylasez3QBU, 4LY4O25080
HP0323Membrane-bound endonuclease (nuc)b’, yO25090
HP0380Glutamate dehydrogenasezP55990
HP0392Histidine kinase, CheAb’O25153
HP0672Member of the PLP-dependent aminotransferase superfamily clan, AspBz3EZSO25383
HP1118γ-Glutamyltranspetptidasea, q, b’, z3FNM, 2QM6, 2QMC, 2NQOO25743
HP1178Purine nucleoside phosphorylase DeoD-typeb’P56463
HP1186Carbonic anhydrasea, q, zO25798
HP1375UDP-N-acetylglucosamine acyltransferase, LpxAz1J2ZO25927
Others
HP0010GroEL, HSP60cP42383
HP0011GroESzP0A0R3
HP0166Response regulator, ArsSzO24973
HP0305Putative human regulator of G protein signaling 12u, bO25076
HP0743Rod shape-determining proteinyP56098
HP1000PARA proteinb’O25646
HP1126Protein TolBbO25751
HP0827ssDNA-binding 12RNP2 precursoru2KI2O25501
HP0835Histone-like DNA-binding protein HUuO25506
HP1v1Ribosomal protein L1uP56029
HP1202Ribosomal protein L11uP66052
Hypothetical proteins
HP0122Hypothetical uncharacterized proteinbP64653, O24940
HP0129Hypothetical uncharacterized proteinuO24943
HP0130Hypothetical uncharacterized proteinb’O24944
HP0135Hypothetical uncharacterized proteinbP64655, O24948
HP0149Hypothetical uncharacterized proteinb’O24960
HP0169Hypothetical secreted colagenasebP56113
HP0204Hypothetical uncharacterized proteinb’O24996
HP0367Hypothetical uncharacterized proteinaO25131
HP0555Hypothetical uncharacterized proteinb’O25382
HP0583Hypothetical uncharacterized proteinb’O25305
HP0659SurA N-terminal domain protein, SurA chaperone of outer membrane proteinsb’O25373
HP0719Hypothetical uncharacterized proteinb’O25421
HP0720Hypothetical uncharacterized proteinuK4NCD4
HP0721Sialic acid-specific adhesion, metal homeostasisi, u2XRHO25423
HP0781Hypothetical uncharacterized proteinb’O25470
HP0783Hypothetical uncharacterized proteinb’O25742
HP0902Hypothetical uncharacterized proteinuO25562
HP0953Hypothetical uncharacterized proteinb’, zO25607
HP0973Hypothetical uncharacterized proteinu, b’O26525
HP1023Hypothetical uncharacterized proteinb’O25270
HP1055Hypothetical uncharacterized proteinb’O25695
HP1056Hypothetical uncharacterized proteinb’O25696
HP1057Hypothetical uncharacterized proteinb’O25697
HP1173Hypothetical uncharacterized proteina, b, zO25787
HP1285lipoprotein, e(P4) familyb’, zO25872
HP1454Hypothetical uncharacterized proteina, zO25993
HP1527Hypothetical uncharacterized proteinb’O26055
HP1580Hypothetical uncharacterized proteinb’O26100
The first column refers to the symbol for strain ACT 700392/26695, the third to the reference, the forth to the PDB ID code if the X-ray structure has been determined, and the fifth to the UniProtKB code. The proteins are grouped according to their function, as explained in the text. a[20], b’[23]; (b refers to proteins having a signal peptide as reported in Supplementary Table mmc4 of reference[23]), c[142], d[84], e[72], f[151], g[152], h[153], i[148], l[74], m[154], n[88], o[112], p[116], q[123], r[119], s[155], t[156], u[21], v[75], w[91], x[102], y[17], z[22].