Epstein-Barr virus-associated lymphoepithelioma-like early gastric carcinomas and endoscopic submucosal dissection: Case series

Figure 3 Endoscopic and pathological features of early lymphoepithelioma-like gastric carcinoma (mimicking a subepithelial tumor) treated by endoscopic submucosal dissection (Case 3). A: White light endoscopy image shows early lymphoepithelioma-like gastric carcinoma (LELC) mimicking a subepithelial tumor; B: Endoscopic ultrasound image shows a homogeneous hypoechoic lesion growing from the muscularis mucosa. Invasion of this lesion into the thickened submucosa layer can also be seen; C: Appearance of the iatrogenic ulcer after endoscopic submucosal dissection; D: Photomicrograph of LELC shows a dense infiltration of lymphocytes in the tumor stroma (HE, × 50); E: Nests of tumor cells separated by a dense infiltration of lymphocytes (HE, × 400); F: In situ hybridization of Epstein-Barr virus-encoded RNA in carcinoma cells (× 50).