Bifidobacterium infantis attenuates colitis by regulating T cell subset responses

Figure 5 mRNA expression of T cell-related cytokines from mesenteric lymph nodes of trinitrobenzene sulfonic acid-induced colitis mice. A: IL-2; B: IFN-γ; C: IL-12p40; D: IL-4; E: RORγt; F: IL-21; G: IL-23; H: IL-17A. Real-time RT-PCR was employed to examine the expression of Th1, Th17 and Foxp3⁺ Treg related cytokines. Control: In the control group, the animals were administered with PBS; Trinitrobenzene sulfonic acid (TNBS)-3: In the TNBS-3 group, the animals were sacrificed 3 d after TNBS induction; TNBS-6: In the TNBS-6 group, the animals were sacrificed 6 d after TNBS induction. Data are from 5 mice per group. Data are expressed as relative expression and the control group was chosen as the calibrator. Data represent mean ± SE. ^aP < 0.05 vs the control group; ^bP < 0.01 vs the control group. IL: Interleukin; IFN: Interferon.