Intravenous vs intraperitoneal mesenchymal stem cells administration: What is the best route for treating experimental colitis?

Figure 3 Mice treated with mesenchymal stem cells presented macroscopic colon characteristics similar to healthy animals. A: Colon length. DSS, DSS-Saline and DSS-MSC IP groups showed a colon length significantly lower than the Naive group; B: Colon weight. DSS-MSC IV group showed significant difference in colon weight compared to DSS group; C: Representative image showing the difference in length between the colons submitted to different treatments. ^bP < 0.01 vs Naive group; ^dP < 0.01 vs DSS group, n = 5 mice/group. DSS: Dextran sulfate sodium; MSC: Mesenchymal stem cell.