Caspase-12 mediates carbon tetrachloride-induced hepatocyte apoptosis in mice

Figure 4 Genotyping and confirmation of the lack of caspase-12 in the caspase-12^-/- mice. A: Genotyping result indicates the absence of wild-type allele and presence of mutant allele in the caspase-12^-/- mice; B: Reverse transcription polymerase chain reaction confirmed the absence of caspase-12 mRNA in caspase-12^-/-; C: Western blot showing the absence of caspase-12 protein in caspase-12^-/- mice.