Non invasive tools for the diagnosis of liver cirrhosis

Table 5 Diagnostic reliability between acoustic radiation force impulse and transient elastography and optimal cut-offs

Ref.	Etiology	Transient elastography						ARFI
		F≥2		F≥3		F = 4		F≥2		F≥3		F = 4
		AUROC	Cu-off kPa	AUROC	Cut-off kPa	AUROC	Cut-off kPa	AUROC	Cut-off m/s	AUROC	Cut-offm/s	AUROC	Cut-offm/s
Friedrich-Rust et al[160]	HCV	0.84		0.91		0.910		0.82	1.37	0.91	1.45	0.91	1.75
Lupsor et al[161]	HCV	0.96	8.1	0.96	0.6	0.97	13.1	0.86	1.34	0.90	1.61	0.94	2.00
Yoneda et al[162]	NASH	-	-	0.99	9.9	0.998	16.0			0.97	1.77	0.97	1.99
Rizzo et al[163]	HCV	0.78	6.5	0.80	8.8	0.8	11.0	0.86	1.3	0.94	1.70	0.89	2.00
Sporea et al[164]	Mixed	0.91				0.99		0.77	1.41	0.79	1.69	0.92	1.81
Sporea et al[165]	HCV	0.82	6.7	0.87	9.6	0.93	11.9	0.81	1.36	0.86	1.47	0.885	1.69
Bota et al[168]	Mixed	0.871	-	-	-	0.931	-	0.851	1.31	-	-	0.931	1.80

¹SROC: Area under the Summary Receiver Operating Characteristic, Meta-analysis. Se: Sensitivity; Sp: Specificity; AUROC: Area Under Receiver Operating Characteristic; F: METAVIR fibrosis score; ARFI: Acoustic radiation force impulse; HCV: Hepatitis C virus; NASH: Nonalcoholic steatohepatitis.