Fluid resuscitation in acute pancreatitis

Table 1 Recommendations in various reviews for fluid resuscitation in acute pancreatitis

Ref.	Type	Conclusion
Tenner et al[7], 2004	Review	250-500 mL/h or more for 48 h
Whitcomb et al[79], 2006	Review	Fluid bolus: maintain hemodynamicsLater: 250-500 mL/h
Otsuki et al[91], 2006	Review	60-160 mL/kg per day1/3 to 1/2 to be given in 6 h
Forsmark et al[96], 2007	Review	Use crystalloids first,Use colloids if hematocrit < 25% or albumin < 2 g/dL
Pandol et al[78], 2007	Review	Severe volume depletion: 500-1000 mL/h; reduce later
Nasr et al[8], 2011	Review	20 mL/kg (1-2 L) in emergency; 150-300 mL/h (3 mL/kg per hour) for 24 h
Trikudanathan et al[49], 2012	Review	Aggressive fluid resuscitation in patients with AP needs to be initiated with therapeutic intent
Haydock et al[49], 2013	Review	Lack of quality evidence to guide most basic aspects of FT providing the equipoise necessary for further RCTs
Wu et al[31], 2013	Review	Institutional protocols must be developed to help ensure adequate fluid resuscitation, particularly in initial 24 h

AP: Acute pancreatitis; FT: Fluid therapy; RCT: Randomized controlled trial.