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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 21, 2014; 20(47): 17863-17876
Published online Dec 21, 2014. doi: 10.3748/wjg.v20.i47.17863
Published online Dec 21, 2014. doi: 10.3748/wjg.v20.i47.17863
Figure 7 Claudin 1 is important for tumor necrosis factor α-induced cell migration in MKN28 cells.
A: Claudin 1 siRNA effectively reduced both the basal and tumor necrosis factor α (TNF-α)-induced expression of claudin 1 mRNA. Mean ± SE. n = 3. aP < 0.05 vs control siRNA, NT; B: Western blotting revealed that transfection of claudin 1 siRNA effectively reduced both the basal and TNF-α-induced expression of claudin 1 protein; C: TNF-α stimulation (20 ng/mL, 48 h) did not enhance cell migration in the claudin 1 siRNA transfected cells. Cell migration was determined by Boyden chamber assay. Mean ± SE. n = 3. NT: No treatment.
- Citation: Shiozaki A, Shimizu H, Ichikawa D, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Iitaka D, Nakashima S, Nako Y, Liu M, Otsuji E. Claudin 1 mediates tumor necrosis factor alpha-induced cell migration in human gastric cancer cells. World J Gastroenterol 2014; 20(47): 17863-17876
- URL: https://www.wjgnet.com/1007-9327/full/v20/i47/17863.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i47.17863