Pathogenesis of alcoholic liver disease: Role of oxidative metabolism

doi:10.3748/wjg.v20.i47.17756

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Dec 21, 2014; 20(47): 17756-17772
Published online Dec 21, 2014. doi: 10.3748/wjg.v20.i47.17756

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Figure 1 Alcohol metabolism. Alcohol dehydrogenase (ADH) is the main cytosolic enzyme that converts alcohol to acetaldehyde. The inducible microsomal enzyme also forms acetaldehyde. The toxic metabolite acetaldehyde is then further oxidized to acetate by the mitochondrial aldehyde dehydrogenase (ALDH).

Citation: Ceni E, Mello T, Galli A. Pathogenesis of alcoholic liver disease: Role of oxidative metabolism. World J Gastroenterol 2014; 20(47): 17756-17772
URL: https://www.wjgnet.com/1007-9327/full/v20/i47/17756.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i47.17756