Differential gene expression profiling of gastric intraepithelial neoplasia and early-stage adenocarcinoma

Table 4 Enriched Gene Ontology categories of the upregulated transcripts in early-stage gastric carcinoma compared with high-grade intraepithelial neoplasia

GO accession	GO term	P value	Genes involved
GO:0050776	Regulation of the immune response	2.27 × 10-8	9
GO:0050851	Antigen receptor-mediated signaling pathway	4.24 × 10-7	5
GO:0002429	Immune response-activating cell surface receptor signaling pathway	5.82 × 10-7	5
GO:0050863	Regulation of T cell activation	6.90 × 10-7	6
GO:0002768	Immune response-regulating cell surface receptor signaling pathway	7.10 × 10-7	5
GO:0050778	Positive regulation of the immune response	3.23 × 10-7	7
GO:0002684	Positive regulation of the immune system process	3.92 × 10-7	8
GO:0001772	Immunological synapse	1.95 × 10-6	3
GO:0051249	Regulation of lymphocyte activation	2.53 × 10-6	6
GO:0042102	Positive regulation of T cell proliferation	2.81 × 10-6	4

GO: Gene ontology.