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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 21, 2014; 20(47): 17863-17876
Published online Dec 21, 2014. doi: 10.3748/wjg.v20.i47.17863
Published online Dec 21, 2014. doi: 10.3748/wjg.v20.i47.17863
Table 1 Genes that displayed the greatest changes in their expressions in the claudin 1 small interfering RNA transfected MKN28 cells
Gene symbol | Gene ID | Gene name | Fold change |
Up-regulated genes | |||
FGF6 | NM_020996 | Fibroblast growth factor 6 | 151.34 |
TM4SF20 | NM_024795 | Transmembrane 4 L six family member 20 | 72.03 |
B4GALNT2 | NM_153446 | Beta-1,4-N-acetyl-galactosaminyl transferase 2 | 47.30 |
SLC2A13 | BC047507 | Solute carrier family 2 (facilitated glucose transporter), member 13 | 43.02 |
HS3ST2 | NM_006043 | Heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 28.39 |
ZNF596 | NM_001042416 | Zinc finger protein 596 | 26.36 |
IL2RA | NM_000417 | Interleukin 2 receptor, alpha | 22.00 |
CCL2 | NM_002982 | Chemokine (C-C motif) ligand 2 | 18.05 |
SGOL2 | BC048349 | Shugoshin-like 2 | 17.64 |
SYT4 | NM_020783 | Synaptotagmin IV | 17.29 |
FGF19 | NM_005117 | Fibroblast growth factor 19 | 16.44 |
ARID5B | NM_032199 | AT rich interactive domain 5B | 14.47 |
DEFB105B | NM_001040703 | Defensin, beta 105B | 14.34 |
DSG3 | NM_001944 | Desmoglein 3 | 12.99 |
RSPH1 | NM_080860 | Radial spoke head 1 homolog (Chlamydomonas) | 12.82 |
COL5A2 | NM_000393 | Collagen, type V, alpha 2 | 12.72 |
NRG2 | NM_013982 | Neuregulin 2 | 12.63 |
TMEM26 | NM_178505 | Transmembrane protein 26 | 12.22 |
CCL3L3 | NM_001001437 | Chemokine (C-C motif) ligand 3-like 3 | 11.54 |
OR51E1 | NM_152430 | Olfactory receptor, family 51, subfamily E, member 1 | 9.43 |
Down-regulated genes | |||
LY6G6F | NM_001003693 | Lymphocyte antigen 6 complex, locus G6F | -332.04 |
WT1 | NM_024426 | Wilms tumor 1 | -68.28 |
MADCAM1 | NM_130760 | Mucosal vascular addressin cell adhesion molecule 1 | -60.84 |
SLC2A9 | NM_001001290 | Solute carrier family 2 (facilitated glucose transporter), member 9 | -48.05 |
SULT4A1 | NM_014351 | Sulfotransferase family 4A, member 1 | -39.30 |
SYNPR | NM_144642 | Synaptoporin | -36.73 |
C10orf47 | NM_153256 | Chromosome 10 open reading frame 47 | -29.96 |
MAS1L | NM_052967 | MAS1 oncogene-like | -29.67 |
CLDN1 | NM_021101 | Claudin 1 | -26.87 |
CBX1 | NM_006807 | Chromobox homolog 1 | -26.37 |
MPPED2 | NM_001145399 | Metallophosphoesterase domain containing 2 | -25.00 |
SCUBE2 | NM_020974 | Signal peptide, CUB domain, EGF-like 2 | -22.13 |
CHI3L2 | NM_001025199 | Chitinase 3-like 2 | -21.67 |
SLIT2 | NM_004787 | Slit homolog 2 | -21.60 |
HFM1 | NM_001017975 | HFM1, ATP-dependent DNA helicase homolog | -20.56 |
CR1 | NM_000651 | Complement component (3b/4b) receptor 1 | -18.04 |
PLA2G10 | NM_003561 | Phospholipase A2, group X | -16.70 |
GRIP2 | NM_001080423 | Glutamate receptor interacting protein 2 | -16.45 |
XIST | NR_001564 | X (inactive)-specific transcript | -15.79 |
TNF-SF10 | NM_003810 | Tumor necrosis factor (ligand) superfamily, member 10 | -15.26 |
- Citation: Shiozaki A, Shimizu H, Ichikawa D, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Iitaka D, Nakashima S, Nako Y, Liu M, Otsuji E. Claudin 1 mediates tumor necrosis factor alpha-induced cell migration in human gastric cancer cells. World J Gastroenterol 2014; 20(47): 17863-17876
- URL: https://www.wjgnet.com/1007-9327/full/v20/i47/17863.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i47.17863